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is there a way to trigger flow X when, for example, flow Y got setup wrongly (like missing parameter or anyway something which prevents Y to even start)?

If FlowY enters a failed / crashed state, create a flow-run for Flow X - it’s hard to specify the exact condition, so it’s not on _why_ it failed, only the state condition it terminates in

<https://docs.prefect.io/2.10.21/cloud/automations/>

this is prefect cloud, we have a self-hosted instance

Unfortunately not, you would need to write some custom interaction to detect a failed flow and take action, likely using the API